Endocrine Abstracts

Background: Articular and psychological complications of acromegaly are known to impair patients’ quality of life (QoL). The aims of this study are: (1) to look for clinical predictors for the progression of the articular and psychological complications, (2) to evaluate the progression of these complications in relation to the activity of the acromegalic disease, and (3) to evaluate how these complications interact to impair the QoL.Material and Met...

Introduction: Prediction of HPA (hypothalamus-pituitary-adrenal) activity after trans-sphenoidal pituitary surgery (NS) is essential for post-operative management. There is not unique behavior in this setting: most of specialists suggests 4-6 weeks of glucocorticoid supplementation and treatment interruption after demonstration of normal endogenous response. Some authors suggest early cortisol detection for the identification of patients requiring glucocorticoid therapy. Aim o...

Over the last two years, COVID-19 outbreak and lockdown have exerted a remarkable psychological burden in the general population. Such an impact is supposed to be even worse in acromegaly, known to induce a severe psychological impairment due to its somatic disfigurements and systemic comorbidities. The current observational study aimed at investigating the impact of COVID-19 outbreak and lockdown on psychological health in acromegalic patients as compared to non-acromegalic h...